Glycosyl compounds
Medchemexpress LLC Uridine, 2'-deoxy-2'-fluoro- | 784-71-4 | 99.9% | 246.19 | 500 MG
2'-Deoxy-2'-fluorouridine is a derivative of the pyrimidine nucleoside uridine. It functions as a nucleoside analog that inhibits the replication of wild-type viruses by binding to the viral RNA. This compound can be incorporated into DNA and RNA in rat and woodchuck models, making it suitable for anti-viral research.
- Inhibits wild-type virus replication
- Binds to viral RNA
- Used in synthesis of RSV polymerase inhibitors
- Incorporates into DNA and RNA in rat and woodchuck models
- Suitable for anti-viral research
Chem-Impex International, Inc. 5-Azacytidine | 320-67-2 | MFCD00006539 | 5G
5-Azacytidine, 320-67-2, MFCD00006539, 5G
Medchemexpress LLC 3-Deazaadenosine | 6736-58-9 | ≥99.0% | 266.26 | 10 MG
3-Deazaadenosine is an inhibitor of S-adenosylhomocysteine hydrolase, with a Ki of 3.9 μM. It exhibits anti-inflammatory, anti-proliferative, and anti-HIV activity.
- Inhibits S-adenosylhomocysteine hydrolase
- Ki of 3.9 μM
- Anti-inflammatory activity
- Anti-proliferative activity
- Anti-HIV activity
- Inhibits p24 antigen in PBMCs infected with HIV-1 isolates
- Inhibits LPS-induced TNF-α mRNA expression
- Enhances nuclear translocation of NF-κB but blocks LPS-induced NF-κB transcriptional activity
- Inhibits phosphorylation of Raf, ERK, protein-dependent kinase 1, protein kinase B (Akt), and forkhead transcription factor FoxO1a
- Suppresses vascular smooth muscle cell (VSMC) proliferation via interfering with Ras signaling
Medchemexpress LLC 1,2,4-triazin-5(2H)-one, 3,4-dihydro-2-β-D-ribofuranosyl-3-thioxo | 27089-56-1 | MFCD00006473 | 97.0% | 261.26 g/mol | C8H11N3O5S | 100 MG
2-Thio-6-azauridine is a thio-substituted azauridine nucleoside provided for research and biochemical assay use. It serves as a modified nucleoside reagent for molecular biology and biochemical studies; identity and purity are supported by analytical data from the certificate of analysis.
Sigma Aldrich Fine Chemicals Biosciences 6-Azauridine | 54-25-1 | MFCD00006472 | 1g
6-Azauridine | Mol Wt: 245.19 | 54-25-1 | MFCD00006472 | 1g
Medchemexpress LLC 1,2,4-triazin-5(2H)-one, 3,4-dihydro-2-β-D-ribofuranosyl-3-thioxo- | 27089-56-1 | MFCD00006473 | 97.0% | 261.26 g/mol | C8H11N3O5S | 50 MG
2-Thio-6-azauridine is a biochemical assay reagent used in research applications. It is a thio analog of 6-azauridine (C8H11N3O5S) with a molecular weight of 261.26 g/mol, supplied as a high-purity solid for laboratory assays. Store under recommended conditions and use for research purposes only.
- High purity (97.0%).
- Molecular formula C8H11N3O5S; molecular weight 261.26 g/mol.
- Intended for biochemical assays and research use only.
- Storage: solid at 4°C; in solvent, store under nitrogen at -80°C (6 months) or -20°C (1 month).
- Supplied as a solid for convenient handling in laboratory workflows.
Apexbio Technology LLC 3-Deazaadenosine(Synonyms: 3-Deazaadenosine, 3-Deaza-adenosine, 3DA, Cordycepin analog, Tubercidin), 10mg, CAS: 6736-58-9.
3-Deazaadenosine (CAS 6736-58-9) is an inhibitor of S-adenosylhomocysteine (SAH) hydrolase an enzyme responsible for the reversible hydrolysis of SAH into adenosine and homocysteine Inhibition of SAH hydrolase by 3-Deazaadenosine (Ki 3 9 M) elevates intracellular SAH concentrations altering the SAH-to-SAM (S-adenosylmethionine) ratio and consequently suppressing SAM-dependent methyltransferase activities In vitro studies demonstrate its antiviral activity against Ebola and Marburg viruses in various primate and mouse cell lines Animal studies indicate protective efficacy against lethal Ebola infection in BALB/c mice Currently 3-Deazaadenosine remains in preclinical research
Sigma Aldrich Fine Chemicals Biosciences 6-Azauridine | 54-25-1 | MFCD00006472 | 5G
6-Azauridine | Purity: >=99% (TLC) | Mol Wt: 245.19 | 54-25-1 | MFCD00006472 | 5G
Medchemexpress LLC 6-azauridine 5'-triphosphate ammonium | 98.0% | 502.16 | C8H17N4O15P3 | 10 MG
6-Azauridine 5′-Triphosphate ammonium is a nucleotide analog of uridine triphosphate supplied as the ammonium salt for biochemical and molecular biology research. The material is provided as a white to off-white solid in a 10 mg presentation with 98.0% purity and is used to study RNA synthesis, transcriptional regulation, and nucleotide metabolism. Store under nitrogen and away from moisture; in solvent, store at -80°C for up to 6 months or -20°C for 1 month.
- Nucleotide analog of uridine triphosphate for biochemical assays.
- Supplied as a white to off-white solid powder.
- High purity: 98.0%.
- Compact 10 mg presentation for small-scale experiments.
- Molecular weight 502.16 and formula C8H17N4O15P3.
- Storage instructions: store under nitrogen and away from moisture; in solvent: -80°C for 6 months, -20°C for 1 month.
Medchemexpress LLC 6-Azauridine triphosphate ammonium | C8H17N4O15P3 | 5 MG
6-Azauridine triphosphate ammonium is a nucleotide analog that resembles uridine triphosphate. It is utilized in research to investigate the mechanisms of RNA synthesis and the regulation of transcription.
- Used to study RNA synthesis
- Used to study transcription regulation
Apexbio Technology LLC 3-Deazaadenosine hydrochloride(Synonyms: 3-Deazaadenosine HCl, C3-Deazaadenosine hydrochloride, 3-Deaza-adenosine hydrochloride), 5mg, CAS: 86583-19-9.
3-Deazaadenosine hydrochloride (CAS 86583-19-9) is a selective inhibitor of S-adenosylhomocysteine hydrolase (SAHH) exhibiting inhibition with a Ki value around 3 9 M It disrupts SAHH-dependent methyl metabolism pathways thereby altering intracellular methyltransferase reactions Due to this biochemical activity it serves as a research agent for studying inflammation cell proliferation and HIV infection as well as investigations into enzyme-mediated methylation processes and related pathological mechanisms